产品货号：
Z26469
中文名称：
Sestrin 2/SESN2抗体
英文名称：
Anti-Sestrin 2/SESN2 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Sestrin 2/SESN2 antibody |
| 指标别名 | HI95;SES2;SESN2;SEST2;Sestrin2;Sestrin-2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ICC/IF,ELISA |
| 基因名称 | SESN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SESN2 recombinant protein (Position:M1-A120). |
| 实际分子量 | 60～66KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SESTRIN2,also known as Hi95,is a member of the sestrin family of PA26-related proteins and is induced following DNA damage or oxidative stress (1).SESTRIN2 and the related protein SESTRIN1 interact with the NRF2 suppressor KEAP1,the autophagy substrate p62 and the ubiquitin ligase RBX1 to protect cells against oxidative stress by activating NRF2 and promoting the p62-dependent autophagic degradation of KEAP1 (2).SESTRIN2 also negatively regulates TOR signaling by activating AMP-activated protein kinase (AMPK) and TSC2 phosphorylation (3),thereby protecting cells against energetic stress-induced death (4). |
| Uniprot ID | P58004 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | Sestrin 2 |
| 蛋白名全称 | Sestrin 2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 |
相关搜索：Sestrin 2/SESN2抗体，Sestrin 2抗体，SESN2多抗，Anti-Sestrin 2/SESN2 antibody